1
97

How Is Thrombophilia Treated?

Every time we cut ourselves and we damage a blood vessel, we obviously bleed; however, soon the bleeding stops. Why? At the damaged vessel`s level, there`s a blood clot, also known as thrombus, which clings to the actual blood vessel and stops the bleeding. Thrombus represents the result of a complex process of coagulation that involves particular proteins, enzymes and cells.

How Is Thrombophilia Treated

Table of Contents

What Is Thrombophilia?

Thrombophilia represents an abnormality that represents a group of disorders that lead to blood clotting. Those who suffer from thrombophilia tend to have blood clots more easily, mostly because their bodies have:

  • Too much of certain proteins, which are known as clotting factors, or;
  • Too little proteins against clots.

Thrombophilia can be inherited or may occur lately when being older. Around 15% of citizens of the U.S. have inherited this abnormality. To contact this infection is a rare phenomenon, but if it happens, it may lead to various risks during pregnancy.

How Does Thrombophilia Manifest?

Other consequences of the illness in youngsters might involve partial or total blindness, through thrombosis of retinal circulation. If experienced by women, the condition is of great relevance in a normal pregnancy`s development. When experience by men, they may produce various forms of impotence through thrombosis of blood vessels which irrigate the genital system and cavernous body.

The illness is relevant to youngsters, because there`re a series of risk factors in them that are relevant. Lots of them practice intense physical activities on a regular basis, such as hiking or diving, under high conditions of pressure, and hypoxia in association with thrombophilia may lead to accidental vascularity. Smoking represents a major factor of risk as well, along with contraception and pregnancy.

From the symptomatology point of view, in mold forms, these medical conditions don`t offer any specific symptom, the illness being able to be detected through an effort thrombosis of rare migraine episodes.

However, in more serious forms patients might experience of decreased limb motor ability, impaired visual field, and episodes of thrombosis and thrombophlebitis with an increased volume of calf or thigh, with decreased functionality and serious pain.

When vascular issues happen in the pulmonary circulation, the patient blames dyspnoea, as well as cardiac thrombosis with retrosternal and precordial pain.

A series of lab and imaging examinations are immediately required in these particular cases.

Types of Thrombophilia

Genetic thrombophilia includes:

  • Factor V Leiden and prothrombin mutations – there are probably the most common types of inherited thrombophilia. They occur from 2% to 7% in Caucasians and more rarely in African-Americans and Asians.
  • Antihrombin, protein C and protein S deficient. Each of them affects less than 1% of people in the U.S.

All these are inherited from an autosomal dominant pattern, meaning that an affected person must inherit the gene from one of her persons. Each child of an affected parent has 50% chances of inheriting thrombophilia.

The most common type of thrombophilia is antiphospholipid syndrome (APS). This occurs in around 5% of pregnant women. In the case of APS, it should be noted that it produces antibodies to attack certain fats (phospholipids), and sometimes clots may even occur. Syndrome designates an autoimmune disease, such as arthritis or lupus erythematosus. Up to 40% from women suffering of this disease have antibodies in the blood, which contribute to the increased risk of certain complications during pregnancy.

Tests

All pregnant women who previously had blood clots should make tests for diagnosing this medical abnormality. Experts may recommend doing these tests if:

  • There`s a previous history in the family regarding thrombophilia before the age of 50.
  • There`s a history of pregnancy complications, including 2 or more miscarriages after the week 10, fetal deaths, premature preeclampsia or other unexplained fetal growth problems.
  • There`s a history of pulmonary thromboembolism or deep vein thrombosis.
  • If a member of the family performed a genetic test and the result came out positive for hereditary thrombophilia.

Treatment

For now, there isn`t any specific treatment for this condition! The present principle of treatment is to offer a specific balance between pro-coagulant and anticoagulant factors. Regarding the measures taken additionally, it`s also advisable to change your lifestyle by simply changing the factors of risk that you can control (smoking, weight loss, etc).

This medical condition, although sometimes is genetically diagnosed, isn`t treated from the beginning unless lab tests show a high risk of developing thrombosis rather soon. The treatment is generally limited to taking aspirin regularly.

The class of medications that are used in patients with symptoms is represented by that of anticoagulants. Most patients are on oral anticoagulation therapy or warfarin, as well as under strict supervision of the attending doctor.

Pregnant women represent a special class, and although they are under correct treatment, some of them might experience many miscarriages until being able to carry a pregnancy until the end, some of them abandoning the idea of having a child naturally completely.

The treatment of the pregnant woman who experiences thrombophilia is Heparin taken daily through injections. Oral anticoagulants or warfarin may go through the placenta and reach the baby, but warfarin can be reintroduced into the treatment while nursing.

Evolution, Complications & Prevention

The evolutions and complications are in relation with the complexity of the condition, age, severity of symptoms, the existence of thrombotic occurrences with various localizations as well as their severity.

Prophylaxis

  • Patients already diagnosed with this condition should avoid any risk factors which favor thrombosis, contraceptives, hypoxia conditions, smoking, prolonged immobilization, etc.
  • Patients with a serious form of this illness as well as who have developed considerable thrombotic accident need to be taken into account for anti-platelet aggregation or chronic anticoagulation with coumarin.

Can Thrombophilia Affect the Way You Give Birth?

If there`re no contraindications and the baby has a weight that corresponds to the pregnancy age, depending on the case evolution, preferably you should talk to the gynecologist about a natural birth or C-section after week 38 of pregnancy. Injection treatment with heparin is stopped with over 12 hours before childbirth.

The presence of this medical condition doesn`t contravene with a natural birth, but the evolution need to be closely supervised. Since most of these pregnancies are hard to get, and followed by treatments which involve discomfort, most often the decision involves a C-section as any unwanted occurrences of the mother or baby are obviously easier to be controlled.

Image courtesy of slideshare.net

Show Comments

359 Comments

  1. RalphLep June 6, 2022
  2. ChesterDyesy June 7, 2022
    • Unrelia May 14, 2023
    • gissuri June 20, 2023
    • oRpCVdPq July 31, 2023
  3. IverDarm June 7, 2022
    • Emikify February 23, 2023
    • Ethigue April 23, 2023
    • embarry May 26, 2023
    • embarry June 6, 2023
    • XPTqJsUo July 4, 2023
    • DAHjoTxpT August 6, 2023
    • JUdigCPq October 27, 2023
  4. Stromvar June 8, 2022
    • Unrelia May 20, 2023
    • gissuri June 27, 2023
    • RrcsxN August 7, 2023
  5. Tppduk June 27, 2022
    • Emikify February 25, 2023
    • Ethigue April 24, 2023
    • embarry May 27, 2023
    • embarry June 8, 2023
    • tThEmGZwm July 6, 2023
    • ZHXGlY August 9, 2023
  6. Eat like a bear diet July 2, 2022
  7. canadian pharmacy cialis August 18, 2022
    • Emikify March 9, 2023
    • Gyngeassy May 5, 2023
    • HYzKVTkU July 17, 2023
    • PsLWGnWYT August 19, 2023
    • Vejoift November 26, 2023
  8. incuchrib August 22, 2022
  9. fupChuddy September 1, 2022
  10. fupChuddy September 2, 2022
    • Emikify March 6, 2023
    • Ethigue May 1, 2023
    • embarry June 2, 2023
    • VAxXtpS July 13, 2023
    • OZuvGoM August 16, 2023
  11. blooguete September 4, 2022
    • Emikify February 23, 2023
    • Ethigue April 23, 2023
    • embarry May 26, 2023
    • embarry June 7, 2023
    • zdlZDiyX July 4, 2023
  12. blooguete September 4, 2022
    • Emikify March 6, 2023
    • Ethigue May 1, 2023
    • embarry June 2, 2023
    • roSHSt July 14, 2023
    • ocyDUU August 16, 2023
  13. Frickus September 6, 2022
    • Emikify March 5, 2023
    • Ethigue April 30, 2023
    • embarry June 1, 2023
    • pYYkdzXT July 13, 2023
    • BGIwzwSA August 15, 2023
    • VUhakIKx October 16, 2023
  14. Frickus September 6, 2022
    • Emikify March 5, 2023
    • Ethigue April 29, 2023
    • embarry June 1, 2023
    • vYAKqPfc July 12, 2023
    • GbqKTFNBJ August 15, 2023
  15. reoloulky September 8, 2022
  16. reoloulky September 8, 2022
    • Emikify February 22, 2023
    • Ethigue April 22, 2023
    • embarry May 25, 2023
    • embarry June 6, 2023
    • FfioaxZ July 3, 2023
    • VPfPctOxv August 6, 2023
    • piomync October 29, 2023
  17. bluelia September 11, 2022
    • Emikify February 27, 2023
    • Ethigue April 26, 2023
    • embarry May 29, 2023
    • embarry June 8, 2023
    • nHZutGCP July 7, 2023
    • RFBAgwKR August 10, 2023
  18. bluelia September 11, 2022
  19. Enrocky September 14, 2022
  20. Enrocky September 14, 2022
    • Emikify March 11, 2023
    • Gyngeassy May 6, 2023
    • yCoJlDg July 18, 2023
    • qbkFvDl August 20, 2023
  21. soifelo September 17, 2022
  22. soifelo September 17, 2022
  23. Link building Services September 30, 2022
  24. Uplindy October 8, 2022
  25. Uplindy October 9, 2022
    • Emikify February 21, 2023
    • Ethigue April 21, 2023
    • embarry May 24, 2023
    • embarry June 5, 2023
    • vXQksJI July 1, 2023
    • sAIJtTNG August 4, 2023
  26. TimothyIntem October 10, 2022
  27. Crurope October 14, 2022
    • Emikify March 2, 2023
    • Ethigue April 28, 2023
    • embarry May 31, 2023
    • ZUInJHH July 11, 2023
    • TsrLRNt August 14, 2023
  28. Crurope October 14, 2022
    • Emikify February 23, 2023
    • Ethigue April 23, 2023
    • embarry May 26, 2023
    • embarry June 6, 2023
    • AjxqGT July 3, 2023
    • gaHSTwDU August 6, 2023
  29. EaseraKap October 30, 2022
  30. Ethislifs November 1, 2022
  31. Ethislifs November 1, 2022
    • Emikify March 5, 2023
    • Ethigue April 30, 2023
    • embarry June 2, 2023
    • VNsiITV July 13, 2023
    • qOMzhr August 16, 2023
  32. driency November 6, 2022
    • Emikify March 5, 2023
    • Ethigue April 30, 2023
    • embarry June 2, 2023
    • AlvBpttIg July 13, 2023
    • RAxzZfbE August 16, 2023
  33. Edittef November 11, 2022
  34. Asseptors November 13, 2022
  35. deelvinia November 15, 2022
  36. Bifaple November 15, 2022
    • Emikify March 8, 2023
    • Gyngeassy May 4, 2023
    • embarry June 3, 2023
    • GvcaCYlA July 15, 2023
    • bJYCiSc August 18, 2023
  37. roarrop November 21, 2022
    • Emikify March 2, 2023
    • Ethigue April 28, 2023
    • embarry May 30, 2023
    • zsuTAgQg July 10, 2023
    • EjrlVP August 13, 2023
    • buy cialis online us October 11, 2023
    • HCmFMiln October 27, 2023
  38. Edgetdype December 8, 2022
  39. blivybiab December 8, 2022
  40. Bonsirl December 9, 2022
  41. Equillalk December 13, 2022
  42. Adopity December 18, 2022
  43. Colin Veal January 22, 2023
  44. Davidopera January 23, 2023
  45. ETHIPMENE January 23, 2023
  46. Engague January 24, 2023
  47. ErrodaY January 25, 2023
  48. amourne January 25, 2023
  49. Saftitams January 26, 2023
  50. Fafeseesk January 26, 2023
  51. gakeldera January 27, 2023
  52. Gypereaph January 27, 2023
  53. ignopay January 28, 2023
  54. jepledo January 29, 2023
  55. Fqxeko February 6, 2023
  56. ETHIPMENE February 9, 2023
  57. Pagiahhom February 11, 2023
  58. insubylib February 11, 2023
  59. Dangext February 13, 2023
  60. Sak February 13, 2023
  61. Knize February 13, 2023
  62. vep February 14, 2023
  63. Insucky February 17, 2023
  64. nercisa February 20, 2023
  65. fefevenly February 22, 2023
  66. Priet February 28, 2023
  67. itemync February 28, 2023
  68. guh April 25, 2023
  69. mynames April 29, 2023
  70. sor May 1, 2023
  71. Den May 3, 2023
  72. Iodindila May 7, 2023
  73. Proxies shared May 8, 2023
  74. Iodindila May 11, 2023
  75. Mic May 17, 2023
  76. proxy elite buy June 10, 2023
  77. Tap June 19, 2023
  78. bezogoroda.ru July 3, 2023
  79. bezogoroda.ru July 5, 2023
  80. bezogoroda.ru July 5, 2023
  81. Vejoift July 19, 2023
  82. McGFAffSB July 22, 2023
  83. yDuDLXs July 27, 2023
  84. teshy December 4, 2023
  85. Zooxy December 25, 2023
  86. пьяный секс January 28, 2024
  87. пьяные порно February 4, 2024
  88. goB February 5, 2024
  89. порно садо мазо February 5, 2024
  90. порно игры бдсм February 6, 2024
  91. БДСМ February 7, 2024
  92. Lob February 8, 2024
  93. писает в рот February 8, 2024
  94. ганг банг February 11, 2024
  95. жесткий анал February 12, 2024
  96. Nat February 12, 2024
  97. девушки секс жмж February 13, 2024
  98. CxufArrek February 16, 2024
  99. Порно в чулках February 17, 2024
  100. сочные жопки February 17, 2024
  101. сквирт зрелых February 18, 2024
  102. Групповое порно February 20, 2024
  103. писсинг видео February 21, 2024
  104. KtbPLUPS February 26, 2024
  105. Smgheive February 26, 2024
  106. Sedcheive March 21, 2024

Leave a Reply